T cell activation

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/08 (2006.01) A61K 38/19 (2006.01) A61K 38/20 (2006.01) C07K 14/52 (2006.01) C12N 5/06 (2006.01) C12P 21/02 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2197801

A method for antigen independent activation of T cells comprising contacting T cells with a combination of cytokines such as two or more of interleukin-2, interleukin-6 and tumour necrosis factor .alpha..

L'invention concerne un procédé d'activation de lymphocytes T sans l'utilisation d'antigène, consistant à mettre les lymphocytes T en contact avec une combinaison de cytokines, comme par exemple deux composés ou davantage choisis parmi l'interleukine-2, l'interleukine-6 et le facteur .alpha. de nécrose des tumeurs.

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