T cell activation markers

Details T cell activation markers T cell activation markers

C - Chemistry, Metallurgy

07

K

530/13, 530/7.1,

C07K 14/47 (2006.01) C07H 21/00 (2006.01) C07K 14/52 (2006.01) C07K 16/28 (2006.01) C12N 15/12 (2006.01)

Patent

CA 1340869

A polypeptide designated H400 and its encoding nucleic acid are provided as markers specific for activated human T cells. Activated T cells are detected immunochemically by monoclonal antibodies specific for H400 or for its immunogenic peptide fragments. Activated T cells are also detected by nucleic acid probes directed to messenger RNA encoding the H400 protein.

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