C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 49/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/86 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2323746
The present invention relates to B7 proteins; to B7 nucleic acid molecules, including those that encode such B7 proteins; to antibodies raised against such B7 proteins; and to therapeutic compounds that regulate B7 function. The present invention also includes methods to identify and obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to regulate an immune response in an animal.
La présente invention concerne des protéines B7, des molécules d'acide nucléique B7, y compris celles qui codent de telles protéines B7, des anticorps dirigés contre de telles protéines B7, et des composés thérapeutiques régulant la fonction B7. La présente invention concerne également des procédés permettant d'identifier et d'obtenir de telles protéines, de telles molécules d'acides nucléiques, de tels anticorps, et de tels composés inhibiteurs. L'invention concerne aussi des compositions thérapeutiques comprenant de telles protéines, de telles molécules d'acides nucléiques, de tels anticorps et/ou de tels composés inhibiteurs ainsi que l'utilisation de telles compositions thérapeutiques permettant de réguler une réponse immunitaire chez un animal.
Sellins Karen S.
Sim Gek-Kee
Yang Shumin
Borden Ladner Gervais Llp
Heska Corporation
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