T-cell epitopes from the oncofetal antigen-immature laminin...

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 14/47 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2606088

The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular several tumor entities including hematological malignancies. The present invention furthermore relates to tumor-associated T-helper cell peptide epitopes, alone or in combination with other tumor-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumor immune responses. In particular, the present invention relates to two novel peptide sequences derived from HLA class I or Il molecules of human oncofoetal antigen immature laminin receptor (OFA/iLR) which can be used in vaccine compositions for eliciting anti-tumor immune responses, namely LLAARAIVAI and ALCNTDSPL.

L'invention concerne des méthodes immunothérapeutiques ainsi que des molécules et des cellules utilisées dans ces méthodes. L'invention concerne, en particulier, l'immunothérapie du cancer, notamment plusieurs entités tumorales comprenant des malignités hématologiques. L'invention concerne également des épitopes peptidiques de lymphocytes T auxiliaires associés à une tumeur, seuls ou en combinaison avec d'autres peptides associés à une tumeur, servant d'ingrédients pharmaceutiquement actifs dans des compositions de vaccins qui stimulent des réponses immunitaires antitumorales. Plus précisément, l'invention concerne deux nouvelles séquences peptidiques dérivées de molécules HLA classe I ou II des récepteurs de la laminine immature d'antigène oncofoetal humain (OFA/iLR) pouvant être utilisées dans des compositions de vaccins pour déclencher des réponses immunitaires antitumorales, à savoir LLAARAIVAI et ALCNTDSPL.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

T-cell epitopes from the oncofetal antigen-immature laminin... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with T-cell epitopes from the oncofetal antigen-immature laminin..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and T-cell epitopes from the oncofetal antigen-immature laminin... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2021298

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.