T-cell epitopes in erythropoietin

Details T-cell epitopes in erythropoietin T-cell epitopes in erythropoietin

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/505 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2494963

The invention relates to the identification of epitopes for T-cells in human EPO as well as T-cell epitope peptides derived from EPO by means of which it is possible to create novel modified EPO variants with reduced immunogenicity.

L'invention concerne l'identification d'épitopes associés aux lymphocytes T dans l'EPO humaine ainsi que des peptides d'épitopes de lymphocytes T dérivés de l'EPO grâce auxquels il est possible de créer de nouveaux variants d'EPO modifiés à immunogénicité réduite.

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