T-cell lymphotrophic virus protein and assay

Details T-cell lymphotrophic virus protein and assay T-cell lymphotrophic virus protein and assay

C - Chemistry, Metallurgy

12

Q

167/140, 530/17,

C12Q 1/70 (2006.01) C07K 14/16 (2006.01) G01N 33/566 (2006.01)

Patent

CA 1283043

T-CELL LYMPHOTROPHIC VIRUS PROTEIN AND ASSAY Abstract of the Disclosure Cells infected with HTLV-III yield a protein (p27) having an apparent molecular weight of about 27,000 daltons. The presence in a biological specimen of p27 antigenic determinants, or of antibodies to p27 antigenic determinants is useful information (by itself or as a panel of tests) for predicting the course of HTLV-III infection in seropositive patients. Polypeptides and antibodies used to perform assays to provide that information are disclosed, as well as assays and kits for such assays.

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