T cell proteins and nucleotides encoding the same

Details T cell proteins and nucleotides encoding the same T cell proteins and nucleotides encoding the same

C - Chemistry, Metallurgy

07

K

C07K 14/54 (2006.01) C12N 15/63 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2580084

The present invention relates to mouse and human J12 polynucleotides, polypeptide and anti J12 antibody molecules. The J12 is a cytokine that is preferentially expressed in Th2 cells. The polypeptides and/or antibodies described herein can be used in methods for detection and treatment of certain autoimmune and inflammatory diseases including asthma.

L'invention concerne des polynucléotides et polypeptides de J12 de souris et d'origine humaine ainsi que des molécules d'anticorps anti-J12. J12 est une cytokine qui est exprimée de préférence dans les cellules Th2. Les polypeptides et/ou anticorps décrits peuvent être utilisés dans des procédés visant à détecter et à traiter certaines maladies auto-immunes et inflammatoires, y compris l'asthme.

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