C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
167/100, 530/15.
C12N 15/18 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61K 38/20 (2006.01) A61K 48/00 (2006.01) A61P 37/04 (2006.01) C07K 14/475 (2006.01) C07K 14/54 (2006.01) C07K 16/22 (2006.01) C07K 16/24 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1341461
The present invention relates generally to a T cell growth factor. More particularly, the present invention relates to a T cell growth factor which comprises a glycoprotein which supports interleukin 2- and interleukin 4- independent growth of helper T cells especially from murine and human sources and further which is capable of augmenting proliferation of IL3- or IL4-responsive cells. Even more particularly, the present invention relates to the helper T cell growth factor P40, pharmaceutical compositions thereof, antibodies thereto and recombinant DNA clones thereof. The present invention also contemplates a method for inducing the proliferation of helper T cells as well as IL3- and Il4-responsive cells. The helper T cells growth factor contemplated herein is useful in the stimulation of specific cells in the immune system, either alone or in combination with IL3 or IL4.
611819
Simpson Richard J.
Uyttenhove Catherine
Van Snick Jacques
Ludwig Institute For Cancer Research
Mcfadden Fincham
Research Corporation Technologies Inc.
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