C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C07K 14/435 (2006.01) C07K 14/705 (2006.01) C12N 15/12 (2006.01)
Patent
CA 2340586
The present invention is directed to isolated nucleic acid molecules encoding pancreatic T-type calcium channels and vectors and host cells comprising such. The invention is further directed to methods and compositions which modulate the expression of pancreatic T-type calcium channels, including antisense. An isolated pancreatic T-type calcium channel protein is provided, as well as antibodies directed to such protein. Pharmaceutical compositions and methods of treatment involving pancreatic T-type calcium channels are also provided.
La présente invention concerne des molécules d'acide nucléique isolées codant des canaux calciques pancréatiques de type T, ainsi que des vecteurs et des cellules hôtes les renfermant. En outre, cette invention concerne des procédés et des compositions qui modulent l'expression des canaux calciques pancréatiques de type T, notamment l'expression antisens. Par ailleurs, cette invention concerne une protéine de canal calcique pancréatique de type T isolée, ainsi que des anticorps dirigées contre cette protéine. Enfin, cette invention concerne des procédés et des compositions pharmaceutiques thérapeutiques impliquant les canaux calciques pancréatiques de type T.
Gowling Lafleur Henderson Llp
South Alabama Medical Science Foundation
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