Tablet composition containing kampo medicinal extract and...

A - Human Necessities – 61 – K

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A61K 47/38 (2006.01) A61K 9/20 (2006.01) A61K 36/00 (2006.01)

Patent

CA 2492156

A tablet composition containing a Chinese orthodox medicine extract, cellulose glycolic acid and sodium hydrogencarbonate. It is preferable that the composition further contains silicic anhydride. A process for producing a tablet composition containing a Chinese orthodox medicine extract which involves the step of adding silicic anhydride and water to the Chinese orthodox medicine extract powder and granulating the mixture under stirring and the step of adding cellulose glycolic acid and sodium hydrogencarbonate to the granulated matter thus obtained. The tablet composition containing a Chinese orthodox medicine extract is excellent in disintegration and elution properties.

La présente invention concerne une composition de comprimé qui contient un extrait issu de la médecine traditionnelle chinoise, de l'acide glycolique et de l'hydrogénocarbonate de sodium. Il est préférable que la composition contienne également de l'anhydride silicique. Le procédé de production de la composition de comprimé contenant l'extrait issu de la médecine traditionnelle chinoise comprend une étape qui consiste à ajouter de l'anhydride silicique et de l'eau à la poudre d'extrait issu de la médecine traditionnelle chinoise et à remuer le mélange pour former une matière granuleuse et une étape qui consiste à ajouter de l'acide glycolique de cellulose et de l'hydrogénocarbonate de sodium à la matière granuleuse ainsi obtenue. La composition de comprimé contenant l'extrait issu de la médecine traditionnelle chinoise est excellent du point de vue de ses propriétés de décomposition et d'élution.

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