Tablet containing coated particles of cetirizine,...

Details Tablet containing coated particles of cetirizine,... Tablet containing coated particles of cetirizine,...

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/137 (2006.01) A61K 31/192 (2006.01) A61K 31/495 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2750196

In one aspect, the present invention features a tablet including a first drug layer and a second drug layer, wherein: (i) the first drug layer includes first drug particles including naproxen and third drug particles including cetirizine, where the first drug particles and/or the third drug particles are coated with an immediate release coating; and (ii) the second drug layer including pseudoephedrine, wherein said second drug layer is a sustained release layer adapted to deliver a therapeutically effective amount of pseudoephedrine for a period of at least twelve hours.

Selon un aspect, la présente invention concerne un comprimé qui comprend une première couche de médicament et une deuxième couche de médicament. Dans le comprimé de l'invention : (i) la première couche de médicament comprend des premières particules de médicament contenant du naproxène et des troisièmes particules de médicament contenant de la cétirizine, les premières particules de médicament et/ou les troisièmes particules de médicament étant enrobées par un revêtement à libération immédiate; et (ii) la deuxième couche de médicament comprend de la pseudoéphédrine, et est une couche à libération prolongée conçue pour administrer une dose efficace sur le plan thérapeutique de pseudoéphédrine pendant une durée d'au moins douze heures.

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