Tablet containing hardly soluble active ingredient

Details Tablet containing hardly soluble active ingredient Tablet containing hardly soluble active ingredient

A - Human Necessities

61

K

A61K 31/407 (2006.01) A61K 9/28 (2006.01) A61K 47/12 (2006.01) A61K 47/38 (2006.01) A61P 25/20 (2006.01)

Patent

CA 2612090

A tablet showing regulated variation in elution from lot to lot which contains from about 3 to about 50% by weight (w/w), based on the whole tablet, of (S)-N- [2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide, magnesium stearate and hydroxypropylcellulose having a viscosity of about 1 to about 4 mPa.s.

La présente invention propose un comprimé dont l'élution de lot à lot varie de manière régulée. Le comprimé contient entre environ 3 et environ 50 % en poids (poids/poids), basé sur le poids total du comprimé, de (S)-N-[2-(1,6,7,8-tétrahydro-2H-indéno[5,4-b]furan-8-yl)éthyl]propionamide, de stéarate de magnésium et d'hydroxypropylcellulose et sa viscosité est comprise entre environ 1 et environ 4 mPa.s.

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