A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/24 (2006.01) A61K 31/519 (2006.01) A61K 47/30 (2006.01)
Patent
CA 2316277
The invention relates to a multilayer tablet for the instant and then prolonged release of active substances comprising at least two superposed layers, characterized in that: a first outer layer is composed of a mixture of excipients and of a first active substance, the said first layer allowing immediate release of the said first active substance; a second layer, arranged in contact with the said first layer, consists of a nonbiodegradable, inert porous polymeric matrix in which a second active substance is dispersed.
La présente invention concerne un comprimé à plusieurs couches conçu pour libérer instantanément et de manière prolongée des principes actifs et comprenant au moins deux couches superposées, caractérisé en ce que la première couche est composée d'un mélange d'excipients et d'un premier principe actif, ladite couche permettant de libérer immédiatement ce premier principe actif, et en ce que la deuxième couche, en contact avec la première, est constituée d'une matrice polymère poreuse inerte non biodégradable, dans laquelle un deuxième principe actif est dispersé.
Orlando Laurence
Saslawski Olivier
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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