A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01)
Patent
CA 2681465
Pharmaceutical formulations containing a salt of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I, which are suitable for forming into a tablet dosage form, as well as tablet dosage forms are disclosed. Disclosed also are methods of treatment utilizing such dosage forms.
L'invention concerne des formulations pharmaceutiques contenant un sel de 8-[{1-(3,5-bis- (trifluorométhyl)phényl)-éthoxy}-méthyl]-8-phényl-1,7-diaza-spiro[4,5]- décan-2-one, représenté par la Formule I, qui peuvent être utilisées pour produire une forme pharmaceutique de type comprimé, ainsi que des formes pharmaceutiques de type comprimé. L'invention décrit également des procédés de traitement utilisant ces formes pharmaceutiques.
Cho Wing-Kee Philip
Qiu Zhihui
Wong Victor Ming-She
Zhao Na
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Opko Health Inc.
Schering Corporation
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