Tablet obtained by direct compression comprising...

Details Tablet obtained by direct compression comprising... Tablet obtained by direct compression comprising...

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/663 (2006.01)

Patent

CA 2415630

A tablet, obtainable by direct compression, comprising the active ingredient 4- amino-1-hydroxybutylidene-1,1-bisphosphonic (alendronic) acid or its pharmaceutically acceptable salts in an amount of 5 to 140 mg, based on the pure acid, a dry binder, a disintegrating agent, a lubricant, the tablet comprising, as the diluent, a combination of at least two diluents except lactose.

L'invention concerne un comprimé obtenu par compression directe et renfermant, en tant qu'ingrédient actif, de l'acide 4-amino-1-hydroxybutylidène-1,1-biphosphonique (alendronique) ou des sels pharmaceutiquement acceptables dudit composé en quantité de 5 à 140 mg, sur la base de l'acide pur, ainsi qu'un liant sec, un désintégrant et un lubrifiant. Comme diluant, ledit comprimé comprend une combinaison d'au moins deux diluants, excepté le lactose.

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