Tablet with multiple drug-containing sections

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/20 (2006.01)

Patent

CA 2619745

A tablet having a double-layer structure composed of layers A and B or a triple-layer structure composed of layers A, B and C in this order, the layer B being a pharmaceutical additive layer, the layers A and C being drug layers and separated from each other by the layer B, each of the layers A and C being held on the layer B and containing the same or different drug; a scored tablet which can provide two pieces each having an equal drug content when divided along one scored line and can provide two pieces each having an unequal drug content when divided along another scored line; and a scored tablet in which any one of cross-sectional surfaces having various drug release controlling functions can be exposed depending on the scored line selected for the division of the tablet.

La présente invention concerne un comprimé ayant une structure à double couche composée de couches A et B ou une structure à triple couche composée de couches A, B et C dans cet ordre, la couche B étant une couche d'additif pharmaceutique, les couches A et C étant des couches de médicaments séparées l'une de l'autre par la couche B, chacune des couches A et C étant tenue sur la couche B et contenant un médicament identique ou différent. L'invention concerne également un comprimé sécable qui peut donner deux morceaux ayant chacun une teneur identique en médicament lorsqu'on le divise le long d'une ligne entaillée et peut donner deux morceaux ayant une teneur différente en médicament lorsqu'on le divise le long d'une autre ligne entaillée; et un comprimé sécable dans lequel une quelconque surface en coupe transversale présentant diverses fonctions de contrôle de libération de médicament peut être exposée en fonction de la ligne entaillée choisie pour diviser le comprimé.

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