Tachykinin antagonists

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 5/06 (2006.01) A61K 31/27 (2006.01) A61K 38/05 (2006.01) C07C 271/20 (2006.01) C07K 5/02 (2006.01) C07K 5/065 (2006.01) C07K 7/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2183991

The small compounds of the instant invention are tachykinin antagonists. The compounds are highly selective and functional NK3 antagonists expected to be useful in the treatment of pain, depression, anxiety, panic, schizophrenia, neuralgia, addiction disorders, inflammatory diseases, gastrointestinal disorders, vascular disorders, and neuropathological disorders.

Les petits composés de la présente invention sont des antagonistes de tachykinine. Lesdits composés sont des antagonistes de NK¿3? hautement sélectifs et fonctionnels utiles dans le traitement de la douleur, de la dépression, de l'anxiété, de la panique, de la schizophrénie, de la névralgie, des troubles de dépendance, des maladies inflammatoires, des troubles gastro-intestinaux, des troubles vasculaires et des troubles neuro-pathologiques.

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