Tailor-made multifunctional stem cells and utilization thereof

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 5/00 (2006.01) A61K 35/12 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61L 27/38 (2006.01) C07K 14/47 (2006.01) C12N 5/02 (2006.01) C12N 5/16 (2006.01) C12N 15/02 (2006.01) C12Q 1/02 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2462619

It is intended to provide cells, tissues and organs each capable of serving as a donor for treating diseases without inducing immunorejection, starting with no egg cell. This object is achieved by providing multifunctional stem cells having a desired genome. These cells are obtained by treating with a reprogramming factor, constructing fused cells of MHC-lacking stem cells with somatic cells, and, after the construction of the fused cells of the stem cells with the somatic cells, eliminating the stem cell-origin genome by a genetic engineering technique, for example, treating with a retrovirus.

La présente invention a pour objet de fournir des cellules, des tissus et des organes pouvant tous servir comme donneur pour traiter des maladies sans induire d'immunoréjection, en commençant sans cellule embryonnaire. Cet objet est réalisé en fournissant des cellules souches multifonctionnelles présentant un génome requis. Ces cellules sont obtenues par un traitement à l'aide d'un facteur de reprogrammation des cellules fusionnées de cellules souches ne possédant pas de CMH avec des cellules somatiques, et après la construction des cellules ainsi fusionnées des cellules souches avec les cellules somatiques, et par l'élimination du génome d'origine de la cellule souche par une technique de génie génétique, par exemple, par un traitement par un rétrovirus.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Tailor-made multifunctional stem cells and utilization thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tailor-made multifunctional stem cells and utilization thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tailor-made multifunctional stem cells and utilization thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1877776

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.