Talaromyces emersonii beta-glucanases

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/56 (2006.01) A01H 5/00 (2006.01) A23K 1/16 (2006.01) A23L 1/28 (2006.01) A61K 38/47 (2006.01) A61P 3/06 (2006.01) C12N 1/15 (2006.01) C12N 9/24 (2006.01) C12N 9/42 (2006.01) C12P 19/14 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2403486

Three novel polypeptides possessing (endo) .beta.-1,4-glucanase activity (EC 3.2.1.4) are disclosed which can degrade cellulose in plant extracts and plant materials. They are thus cellulases and can cleave .beta.-D-glucan polymers at internal (1-3, 1-4 or 1-6) bonds between adjacent glucose units. The amino acid sequence and encoding DNA sequence is given of all 3 glucanases (CEA, CEB and CEC) which were obtained from the fungal strain Talaromyces emersonii. The glucanases can be used to treat cellulose in the preparation of edible foodstuffs and animal feed.

Cette invention a trait à trois nouveaux polypeptides dotés d'une endoactivité .beta.-1,4-glucanase (EC 3.2.1.4), lesquels polypeptides sont en mesure de dégrader la cellulose dans des extraits de végétaux et des végétaux. Il s'agit de cellulases pouvant couper des polymères de .beta.-D-glycanne au niveau des liaisons internes (1-3, 1-4 ou 1-6) entre des motifs glucoses adjacents. La séquence aminoacide et la séquence d'ADN codante concernent les trois glucanases (CEA, CEB et CEC) obtenues à partir de la souche fongique Talaromyces emersonii. Il est possible d'utiliser ces glucanases pour traiter de la cellulose lors de la préparation de produits alimentaires et d'aliments pour animaux.

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