Tamandarin analogs and fragments thereof and methods of...

A - Human Necessities – 61 – K

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A61K 38/12 (2006.01) C07K 5/00 (2006.01) C07K 7/00 (2006.01) C07K 16/00 (2006.01) C07K 17/00 (2006.01)

Patent

CA 2519234

The present invention is directed to a compound of Formula I wherein R1, R2, R3, R4, R5, R6, W, X, Y, and Z are defined herein. The compounds of the present invention are useful as anticancer agents. Specifically, the compounds are useful for treating or preventing cancer and tumor growth. The present invention is also directed to compositions comprising a compound according to the above formula. The present invention is also directed to methods of using a compound according to the above formula.

La présente invention concerne un composé de formule I, dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, W, X, Y, et Z sont définis tels que mentionnés. Ces composés sont utilisés en tant qu'agents anticancéreux. Notamment, lesdits composés sont utilisés dans le traitement ou la prévention de cancer et de croissance tumorale. Ladite invention a aussi trait à des compositions contenant un composé de la formule susmentionnée, ainsi qu'à des méthodes d'utilisation d'un composé de la formule ci-dessus.

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