Tamoxifen as a therapy to reduce irinotecan...

A - Human Necessities – 61 – K

Patent

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A61K 31/138 (2006.01) A61P 1/12 (2006.01)

Patent

CA 2280855

The present invention provides a method for preventing or decreasing diarrhea associated with irinotecan administration comprising the administration of tamoxifen at least two cell cycles prior to irinotecan administration.

Cette invention a trait à une méthode visant à prévenir ou à atténuer une diarrhée liée à une administration d'irinotecan, laquelle méthode consiste à administrer du tamoxifène au moins deux cycles cellulaires avant l'administration d'irinotecan.

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