Tamper resistant lipid-based oral dosage form for opioid...

A - Human Necessities – 61 – K

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A61K 47/44 (2006.01) A61K 9/50 (2006.01) A61K 47/06 (2006.01)

Patent

CA 2689434

A tamper resistant drug delivery system made of at least one lipid, at least one gelling agent and at least one drug active, such as oxycodone, where the system gels rapidly in the presence of water or a solution containing water, and the drug active releases into the digestive system, wherein the weight ratio of gelling agent to lipid is less than 1:1.4.

L'invention concerne un système d'administration de médicaments inviolable comprenant au moins un lipide, au moins un agent gélifiant et au moins un médicament actif, tel que l'oxycodone, le système de gel gélifiant rapidement en présence d'eau ou d'une solution contenant de l'eau, et les libérations actives de médicament dans l'appareil digestif, le rapport en poids de l'agent gélifiant sur lipide étant inférieur à 1:1,4.

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