Tan-1511, its derivatives, production and use thereof

Details Tan-1511, its derivatives, production and use thereof Tan-1511, its derivatives, production and use thereof

C - Chemistry, Metallurgy

12

P

C12P 21/02 (2006.01) A61K 38/04 (2006.01) C07C 323/59 (2006.01) C07K 5/04 (2006.01) C07K 5/06 (2006.01) C07K 5/083 (2006.01) C07K 5/103 (2006.01) C07K 7/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2112522

ABSTRACT OF THE DISCLOSURE Disclosed are a compound of the formula: Image wherein each R1, R2 and R3 is an aliphatic acyl group, X is an amino acid sequence consisting of 1 to 5 amino acid residues which contain at least one acidic amino acid residue, n is an integer of 0 to 4, provided that when n is 0, X has glutamyl- glycyl at its N-terminal and when n is 1 or 2, the acidic amino acid residue is an acidic amino acid residue other than D-glutamyl, or a salt thereof, which is useful as a therapeutic agent of leukocytopenia.

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