C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01)
Patent
CA 2526907
The present invention provides methods of discovering and mapping secondary binding sites on biological molecules (e.g., proteins), the effects, if any, of site occupancy on the primary function of the molecule, and the screening of small molecules against the secondary binding sites. The invention further provides novel complexes for modification of secondary binding sites and the resulting modified biological molecules.
La présente invention concerne des procédés pour découvrir et cartographier des sites de liaison secondaires sur des molécules biologiques (par ex. des protéines), les effets, s'il y en a, d'une occupation de site sur la fonction primaire de la molécule, et pour cribler des petites molécules contre les sites de liaison secondaires. La présente invention concerne également de nouveaux complexes pour modifier des sites de liaison secondaires, ainsi que les molécules biologiques modifiées résultantes.
Advanced Proteome Therapeutics Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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