Tankyrase, a trfi binding protein

Details Tankyrase, a trfi binding protein Tankyrase, a trfi binding protein

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A01K 67/027 (2006.01) A61K 38/45 (2006.01) C07K 16/40 (2006.01) C12N 9/10 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2331372

The present invention discloses a unique vertebrate protein, tankyrase that binds to telomeric repeat binding factor 1 (TRF1). Nucleic acids encoding tankyrases are also disclosed. Methods of scrreening drugs using tankyrase are also included.

L'invention concerne une protéine unique de vertébré, la tankyrase, qui se lie au facteur 1 de liaison de répétition télomérique (TRF1). Des acides nucléiques codant pour des tankyrases sont également décrits. L'invention concerne également des procédés de criblage de médicaments utilisant une tankyrase.

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