Targeted artificial gene delivery

Details Targeted artificial gene delivery Targeted artificial gene delivery

C - Chemistry, Metallurgy

12

N

C12N 15/87 (2006.01) A61K 9/127 (2006.01) A61K 9/50 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C12N 15/86 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2380517

Novel and improved compositions and methods for gene therapy are provided. In particular, a targeted artificial gene delivery ("TAGD") vehicle is provided, comprising a multifunctional artificial surface moiety surrounding a recombinant viral particle (nucleocapsid) or recombinant core for gene delivery.

L'invention concerne des compositions et procédés, nouveaux et améliorés, destinés à la thérapie génique. Elle concerne notamment un véhicule d'apport ciblé de gène artificiel comprenant une partie de surface artificielle polyvalente entourant une particule virale recombinée (nucléocapside) ou un noyau recombiné, aux fins d'apport de gène.

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