C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2748161
The invention relates to targeted binding agents against .alpha.5.beta.1 and uses of such agents. More specifically, the invention relates to fully human monoclonal antibodies directed to .alpha.5.beta.1. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of .alpha.5.beta.1 and as diagnostics.
La présente invention concerne des agents de liaison ciblés contre a5ß1 et leurs applications. Plus spécifiquement, la présente invention concerne des anticorps monoclonaux entièrement humains dirigés contre a5ß1. Les agents de liaison ciblés selon l'invention peuvent être employés dans le traitement de pathologies associées à l'activité et/ou la surproduction de a5ß1, ainsi qu'en tant qu'agents de diagnostic.
Alfred Avril
Barry Simon Thomas
Eberlein Catherine Anne
Foltz Ian
Kang Paul
Astrazeneca Ab
Smart & Biggar
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