C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01)
Patent
CA 2657898
Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of PDGFR-alpha.
L'invention concerne des agents liants ciblés dirigés contre l'antigène PDGFR-alpha, ainsi que les utilisations de ces agents. L'invention concerne plus particulièrement des anticorps monoclonaux entièrement humains dirigés contre l'antigène PDGFR-alpha, ainsi que les utilisations de ces anticorps. Des aspects de l'invention concernent également des hybridomes ou autres lignées cellulaires exprimant ces anticorps. Les agents liants ciblés et les anticorps selon l'invention sont utiles dans le diagnostic et le traitement de maladies associées à l'activité et/ou à la surexpression de PDGFR-alpha.
Blakey David Charles
Cartlidge Susan Ann
Foltz Ian
Gazit-Bornstein Gadi
Kang Jaspal Singh
Astrazeneca Ab
Smart & Biggar
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