A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 31/7056 (2006.01) A61P 31/12 (2006.01)
Patent
CA 2566874
This invention relates to targeted delivery of anti-viral compounds through protein bioconjugation. More particularly, it relates to an anti-viral compound conjugated to hemoglobin and to a method of treating a viral infection using said conjugate. The invention also provides a method of targeted drug delivery of an anti-viral nucleoside analogue to macrophages, cells comprising a hemoglobin receptor and to CD163 bearing cells.
L'invention concerne l'administration ciblée de composés antiviraux au moyen de bioconjugués protéiques. Elle concerne plus particulièrement un composé antiviral conjugué à de l'hémoglobine et une méthode de traitement d'une infection virale au moyen dudit conjugué. Elle concerne également une méthode d'administration ciblée d'un analogue de nucléoside antiviral à des macrophages, à des cellules comprenant un récepteur de l'hémoglobine et à des cellules comportant CD163.
Adamson Gordon J.
Bell David
Biessels Peter
Ng Nancy
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hemosol Lp
Therapure Biopharma Inc.
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