Targeted delivery of virus vector to mammalian cells

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 7/00 (2006.01) A61K 47/00 (2006.01) A61K 48/00 (2006.01) C12N 15/64 (2006.01) C12N 15/86 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2122613

A complex between a virus the cell binding receptor of which has been inactivated and an antibody, said antibody having the ability to interact with a specific antigen on the surface of a mammalian cell different from the cellular structure which would otherwise mediate binding of the virus to the cell surface and which antigen has the ability to mediate entrance of a virus vector or infectious virus into mammalian cells.

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