Targeted gene addition in stem cells

Details Targeted gene addition in stem cells Targeted gene addition in stem cells

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01)

Patent

CA 2605324

The present invention provides methods for adenoassociated virus- mediated site-specific integration of a transgene into a stem cell. Stem cells having a transgene integrated therein, and differentiated cells generated from the stem cells are also provided.

L'invention concerne des procédés destinés à l'intégration spécifique de site induite par un virus adénoassocié d'un transgène dans une cellule embryonnaire. L'invention concerne également des cellules embryonnaires possédant un transgène intégré, et des cellules différenciées générées à partir de ces cellules embryonnaires.

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