Targeted hysteresis hyperthermia as a method for treating...

A - Human Necessities – 61 – K

Patent

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A61K 41/00 (2006.01) A61K 9/50 (2006.01) A61N 1/40 (2006.01) A61N 2/04 (2006.01)

Patent

CA 2253963

A method for site specific treatment of diseased tissue in a patient, comprising the steps of: (i) selecting at least a magnetic material which has a magnetic heating efficiency of at least about 4.5 x 10-8 J.m./A.g, when magnetic field conditions are equal to or less than about 7.5 x 107 A/s; (ii) delivering the magnetic material to diseased tissue in a patient; and (iii) exposing the magnetic material in the patient to a linear alternating magnetic field with a frequency of greater than about 10 kHz and a field strength such that the product of field strength, frequency and the radius of the exposed region is less than about 7.5 x 107 A/s to generate hysteresis heat in the diseased tissue.

L'invention porte sur un procédé de traitement spécifique à un site de tissus lésés d'un patient, comportant les étapes suivantes: (i) sélection d'au moins un matériau magnétique présentant une capacité de réchauffage magnétique d'au moins environ 4,5 x 10?-8¿ J.m./A.g, pour un champ magnétique égal ou inférieur à 7,5 x 10?7¿ A/s; (ii) introduction du matériau magnétique dans les tissus lésés du patient; et (iii) exposition du matériau magnétique placé dans le patient à un champ magnétique linéaire alternatif d'une fréquence supérieure à environ 10 kHz et d'une intensité telle que le produit de l'intensité du champ par la fréquence et par le rayon de la zone exposée soit inférieur à environ 7,5 x 10?7¿ A/s de manière à produire de la chaleur par hystérèse dans les tissus lésés.

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