Targeted identification of immunogenic peptides

Details Targeted identification of immunogenic peptides Targeted identification of immunogenic peptides

G - Physics

01

N

G01N 33/53 (2006.01)

Patent

CA 2622036

This invention relates generally to identifying peptide sequences involved in antibody binding to any protein for synthesis of vaccine treatments. This novel method allows for a more manageable vaccine peptide discovery and specific generation of unique immunogenic peptides from self-tumor associated proteins and/or foreign proteins from infectious organisms for specific and/or enhanced expression only in the presence of the antibody.

Cette invention porte, de manière générale, sur l'identification de séquences peptidiques intervenant dans la liaison d'anticorps à toute protéine dans la synthèse des thérapies vaccinales. Cette nouvelle méthode permet de rechercher des peptides vaccinaux plus gérables et une génération spécifique de peptides immunogènes uniques provenant d'autoprotéines associées à des tumeurs et/ou de protéines exogènes provenant d'organismes infectieux pour obtenir une expression spécifique et/ou améliorée uniquement en présence de l'anticorps.

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