Targeted integration into stem cells

Details Targeted integration into stem cells Targeted integration into stem cells

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) C12N 15/00 (2006.01) C12N 15/85 (2006.01) C12N 15/90 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) C12N 15/113 (2010.01)

Patent

CA 2756833

Disclosed herein are methods and compositions for targeted integration of sequences of interest such as lineage-specific or cell fate reporter constructs or protein encoding sequences into stem cells.

L'invention concerne des procédés et des compositions pour l'intégration ciblée de séquences d'intérêt, telles que des constructions spécifiques à une lignée ou rapporteuses du destin de cellules ou des séquences codant pour des protéines, dans des cellules souches.

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