C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/87 (2006.01) A61K 9/107 (2006.01) A61K 47/06 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07K 17/00 (2006.01) C12N 15/10 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2379431
Targeted lipids and lipid particles are described which are assemblies of multipolar lipids, targeting molecules such as antibodies and polyanions. The lipids are of particular use for the delivery of bioactive substances such as nucleic acids to cells in vitro and especially in vivo.
L'invention concerne des lipides et des particules lipidiques cibles constituant des ensembles de lipides multipolaires, de molécules de ciblage comme les anticorps et de polyanions. Les lipides sont utilisés, en particulier, dans l'administration de substances bioactives, par exemple des acides nucléiques, à des cellules in vitro et particulièrement in vivo.
Baker Terence Seward
Catterall Catherine Fiona
Eaton Michael Anthony William
Norman Timothy John
Parker David
Celltech R&d Limited
Kirby Eades Gale Baker
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