Targeted oxygen delivery via intravenous or intra-arterial...

Details Targeted oxygen delivery via intravenous or intra-arterial... Targeted oxygen delivery via intravenous or intra-arterial...

A - Human Necessities

61

K

A61K 38/42 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2690603

A method of delivering oxygen to a tissue, a blood vessel, an organ, or a region of an organ, under an ischemic condition, or prophylactically preventing occurrence of an ischemic condition, of a subject, comprising the step of administering to the subject an oxygenated hemoglobin solution, wherein the oxygenated hemoglobin solution includes polymerized hemoglobin, and wherein about 80% by weight, or greater, of the polymerized hemoglobin is oxyhemoglobin.

L'invention porte sur un procédé de distribution d'oxygène à un tissu, un vaisseau sanguin, un organe ou une région d'un organe d'un sujet, dans une condition ischémique, ou de prévention de manière prophylactique de l'apparition d'une condition ischémique. Ce procédé comprend l'étape consistant à administrer au sujet une solution d'hémoglobine oxygénée, la solution d'hémoglobine oxygénée comprenant de l'hémoglobine polymérisée, et environ 80 % en poids, ou plus, de l'hémoglobine polymérisée étant de l'oxyhémoglobine.

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