A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 38/13 (2006.01)
Patent
CA 2079590
2079590 9213569 PCTABS00014 The structure and the manner of manufacture of polymeric conjugates of cyclosporin, characterized in that they as polymeric carriers contain 40-700 polymerized monomeric units composed from 20-99 % mol. biologically inert hydrophilic units, such as N-(2-hydroxypropyl)methacrylamide, N-vinylpyrrolidone, or acrylic and methacrylic acid in the form of sodium salts, 0.1-25 % mol. units of methacryloylated amino acids or methacryloylated oligopeptides with terminally bound cyclosporin and 0-10 % mol. units of methacryloylated amino acids or oligopeptides, with an antibody bound to them as the determinant of transport to the targeted cells.
Fornusek Lubor
Jegorov Alexandr
Matha Vladimir
Rihova Blanka
Strohalm Jiri
Galena
Robic
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