Targeted polymeric prodrugs containing multifunctional linkers

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 65/329 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 17/08 (2006.01) C12N 11/08 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2662981

The present invention provides single chain antibody-directed polymeric prodrugs containing multifunctional linkers. Methods of making the polymeric delivery systems and methods of treating mammals using the same are also disclosed.

L'invention concerne des promédicaments polymères, dirigés contre des anticorps monocaténaires, qui contiennent des segments multifonctionnels. L'invention concerne en outre des procédés de mise au point de systèmes de distribution polymères ainsi que des méthodes de traitement de mammifères faisant intervenir ces derniers.

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