A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 9/00 (2006.01) A61K 9/50 (2006.01) A61K 9/66 (2006.01) A61K 31/70 (2006.01) A61K 41/00 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) C12N 15/11 (2006.01) C12N 15/87 (2006.01)
Patent
CA 2248158
The invention relates to a new and improved pharmaceutical composition and method for delivery of therapeutic agents. The methods and composition of the invention can be used with several therapeutic agents and can achieve site specific delivery of a therapeutic substance. This can allow for lower doses and for improved efficacy with drugs which traditionally reach targeted sites and can result in utility for agents such as oligonucleotides which are plagued with problems in reaching targeted sites in necessary therapeutic levels.
La présente invention concerne une composition pharmaceutique innovante et améliorée ainsi qu'un procédé d'apport d'agents thérapeutiques. Les procédés et la composition de l'invention, qui conviennent pour l'utilisation de nombreux agents thérapeutiques, permettent de réaliser sur un site spécifique un apport de substance thérapeutique. Cela permet d'utiliser des doses moins importantes et accroît l'efficacité de médicaments qui atteignent traditionnellement des sites ciblés. Cela peut s'avérer utile pour des agents tels que les oligonucléotides pour qui lesquels est difficile d'atteindre des site ciblés en des quantités thérapeutiques suffisantes.
Iversen Patrick L.
Meyer Gary D.
Porter Thomas R.
Gowling Lafleur Henderson Llp
The Board Of Regents Of The University Of Nebraska
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