A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2533540
The object of the invention is an immunogenic composition characterized in that it comprises a vehicle and conjugates as an antigenic structure,said conjugates fully or partially comprising amino acid sequences of at least one peptide derived from an extracellular loop of protein P-170. Each peptide is associated with several molecules of fatty acid of a carbon chain ranging from C12 to C24 in order to enable the induction of anti-P-170 antibodies in appropriate conditions of administration. The invention relates to said composition for the definition of multidrug resistance treatment means.
L~invention a pour objet une composition immunogène caractérisée en ce qu~elle comprend d~une part un véhicule et d~autre part, en tant que structure antigénique, des conjugués comprenant tout ou partie des séquences d~acides aminés d~au moins un peptide dérivé d~une boucle extracellulaire de la protéine P-170, chaque carbonée comprise entre C12 et C24 pour, dans des conditions d~administration appropriées, permettre l~induction d~anticorps anti-P-170. L~invention concerne ladite composition pour la définition de moyens de traitement des résistances multidrogues.
Hickman David T.
Madoulet Claudie
Nicolau Claude
Tosi Pierre-Francois
Ac Immune S.a.
Goudreau Gage Dubuc
Universite de Reims
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