Targeted therapeutics and uses thereof

Details Targeted therapeutics and uses thereof Targeted therapeutics and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 498/22 (2006.01) A61K 31/133 (2006.01) A61K 31/196 (2006.01) A61K 31/42 (2006.01) A61K 31/4409 (2006.01) A61K 31/4965 (2006.01) A61K 31/535 (2006.01) A61K 31/7048 (2006.01) A61K 45/00 (2006.01) A61K 47/48 (2006.01) A61P 9/10 (2006.01) A61P 31/00 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01) A61P 31/12 (2006.01) A61P 33/02 (2006.01) A61P 43/00 (2006.01) C07D 498/08 (2006.01)

Patent

CA 2465846

The invention features a method of delivering a drug to a diseased cell by linking the drug to a rifamycin derivative, compositions that include drug- rifamycin conjugates of the invention, and methods for treating disease using those composition.

L'invention concerne une méthode d'administration d'un médicament dans une cellule malade par liaison de ce médicament à un dérivé de rifamycine. L'invention concerne également des compositions comprenant les conjugués médicament-rifamycine de l'invention, ainsi que des méthodes de traitement d'une maladie au moyen de ces compositions.

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