Targeted therapeutics based on engineered proteins for...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) C07K 14/78 (2006.01) C12N 9/12 (2006.01) C12N 15/10 (2006.01) C40B 40/02 (2006.01)

Patent

CA 2670471

The present invention provides innovative proteins that bind to insulin-like growth factor-I receptor (IGF-IR), as well as other important proteins. The invention also provides innovative proteins in pharmaceutical preparations and derivatives of such proteins and the uses of same in diagnostic, research and therapeutic applications. The invention further provides cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and vectors comprising the polynucleotides encoding the innovative proteins.

La présente invention concerne des protéines innovantes qui se lient au récepteur du facteur de croissance de type insulinique I (IGF-IR), ainsi qu'à d'autres protéines importantes. L'invention concerne également des protéines innovantes incorporées dans des préparations pharmaceutiques et des dérivés de telles protéines ainsi que leurs utilisations à des fins de diagnostic, de recherche et de thérapie. L'invention concerne en outre des cellules comprenant de telles protéines, des polynucléotides codant pour de telles protéines ou leurs fragments et des vecteurs comprenant des polynucléotides codant pour ces protéines innovantes.

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