Targeted transgenesis of short hairpin rna expression...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/90 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2573117

The invention provides a method for targeted transgenesis of short hairpin RNA expression cassettes using recombinase mediated cassette exchange. Suitable nucleotide acid sequences and vectors for the targeted transgenesis and recombinase mediated transgenesis are provided.

Cette invention concerne un procédé de transgénèse ciblée de cassettes d'expression d'ARN court en épingle à cheveux utilisant un échange de cassettes induit par la recombinase. Cette invention concerne également des séquences d'acides nucléotidiques et des vecteurs appropriés pour la transgénèse ciblée et la transgénèse induite par la recombinase.

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