Targeting cells with altered microrna expression

Details Targeting cells with altered microrna expression Targeting cells with altered microrna expression

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2610702

The present invention relates to a method of modulating development of a cell. The method includes the step of introducing into the cell a nucleic acid with the capacity to modulate development of the cell, the nucleic acid including a target site for binding of a microRNA, wherein the activity and/or concentration of the microRNA in the cell results in a level of activity and/or concentration of the nucleic acid in the cell sufficient to modulate development of the cell.

L'invention porte sur un procédé qui permet de moduler le développement d'une cellule. Le procédé consiste à introduire dans la cellule un acide nucléique capable de moduler le développement de la cellule, ledit acide nucléique comprenant un site cible destiné à la liaison d'un microARN, l'activité et/ou la concentration du microARN dans la cellule entraînant un niveau d'activité et/ou de concentration de l'acide nucléique dans la cellule suffisant pour moduler le développement de la cellule.

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