Targeting of antigen presenting cells with...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01)

Patent

CA 2740162

The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immuse response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface. The nanocarriers are capable of targeting antigen presenting cells when administered to a subject. The invention provides pharmaceutical compositions comprising nanocarriers. The present invention provides methods of designing, manufacturing, and using nanocarriers and pharmaceutical compositions thereof.

La présente invention concerne des compositions et des systèmes de délivrance de nanosupports à des cellules du système immunitaire. Linvention concerne des nanosupports capables de stimuler une réponse immunitaire dans les lymphocytes T et/ou dans les lymphocytes B. Linvention concerne des nanosupports qui comprennent une surface de caractère immun. Les nanosupports sont capables de cibler des cellules présentant lantigène lorsquils sont administrés à un sujet. Linvention concerne des compositions pharmaceutiques renfermant des nanosupports. La présente invention a pour objet des méthodes de conception, de fabrication et dutilisation de nanosupports et de leurs compositions pharmaceutiques.

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