Targeting of liposomes to the blood-brain barrier

Details Targeting of liposomes to the blood-brain barrier Targeting of liposomes to the blood-brain barrier

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 9/127 (2006.01)

Patent

CA 2141216

The present invention is directed to the targeting of drugs, peptides, and proteins to the brain. Liposomes containing the compound to be delivered are coupled to antibody binding fragments which bind to receptors on the vascular endothelium of the blood-brain barrier. The targeted receptors include transferrin receptor, insulin receptor, IGF-I and IGF-II receptors, among others. Also provided are pharmaceutical compositions and methods for administering the drugs to a subject in need by means of the receptor-targeted immunoliposomes.

Affiliated with

Also associated with

Rating

Targeting of liposomes to the blood-brain barrier does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Targeting of liposomes to the blood-brain barrier, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Targeting of liposomes to the blood-brain barrier will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1962918