Targeting somatic gene therapy to joints

Details Targeting somatic gene therapy to joints Targeting somatic gene therapy to joints

A - Human Necessities

61

K

A61K 48/00 (2006.01) A01K 67/027 (2006.01) A61K 47/48 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C12N 5/10 (2006.01) C12N 9/06 (2006.01) C12N 9/12 (2006.01) C12N 9/14 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01) C12N 15/88 (2006.01) C12Q 1/02 (2006.01) G01N 33/48 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2139948

A method of transfecting a cell in a structure of a joint is disclosed, wherein a DNA vector containing a nucleic acid cas- sette encoding, for example, a cell ablation agent or a therapeutic agent, is directly injected into the joint. The invention also in- cludes a transfected synovial cell.

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