C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/46, 530/17.0
C07D 207/46 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07D 207/404 (2006.01) C07D 207/452 (2006.01) C07H 15/203 (2006.01) C07H 15/252 (2006.01) C07K 17/02 (2006.01)
Patent
CA 2000039
- 48 - ABSTRACT OF THE DISCLOSURE TARGETING SUBSTANCE-DIAGNOSTIC/THERAPEUTIC AGENT CONJUGATES HAVING SCHIFF BASE LINKAGES Targeting substance-diagnostic/therapeutic agent conjugates joined by stabilized Schiff base or hydrazone linkages are disclosed. In addition, slow release carrier-drug pharmaceuticals are described. The diagnostic and therapeutic conjugates and pharmaceuticals of the present invention provide certain advantages relating to in vivo administration, including controlled release of the active agent at a target site.
Brixner Diana I.
Comezoglu F. Taha
Morgan A. Charles
Morgan A. Charles Jr.
Reed Michael W.
Brixner Diana I.
Comezoglu F. Taha
Johnson Ernest Peter
Morgan A. Charles
Morgan A. Charles Jr.
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