Tartaric acid monoesters of optically active alkanols and...

C - Chemistry – Metallurgy – 07 – D

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260/486.2, 260/3

C07D 295/14 (2006.01) C07C 275/38 (2006.01) C07D 209/88 (2006.01)

Patent

CA 1239646

ABSTRACT OF DISCLOSURE The present invention relates to tartaric acid monoesters of optically active alkanolamines of the general formula Image I in which A represents an optionally substituted phenyl, naphthyloxymethyl, indolyloxymethyl radical or a substituted phenyloxymethyl radical of the formula Image in which R3 represents a methoxyethyl radical or the radical -HN-acyl, acyl being defined as a lower alkanoyl radical having not more than 4 carbon atoms or as a dialkylcarbamoyl radical in which alkyl has 1 or 2 C atoms, and R4 denotes hydrogen or the radical CH3CO-, R2 represents hydrogen or a branched alkyl radical having 3 or 4 C atoms and R1 represents the radical of a disubstituted (R,R)- or (S,S)-tartaric acid of the general formula HOOC - CH(OR5)-CH(OR5)-CO- II wherein R5 denotes an alkyl, aralkyl, optionally substituted alkanoyl, optional-ly substituted aroyl or substituted vinyl radical or an N-arylcarbamoyl radical,and also salts thereof with acid or bases.

461001

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