Taste-masked drugs in rupturing multiparticulates

Details Taste-masked drugs in rupturing multiparticulates Taste-masked drugs in rupturing multiparticulates

A - Human Necessities

61

K

A61K 9/50 (2006.01)

Patent

CA 2561855

A pharmaceutical composition comprises multiparticulates comprising a drug, a matrix material, and swelling agent. In one aspect, the multiparticulates comprise a core comprising a drug, and a coating surrounding the core. The coating is selected from the group consisting of (i) a water-permeable, substantially drug-impermeable coating, and (ii) an anti-enteric coating.

L'invention concerne une composition pharmaceutique comprenant des matières particulaires multiples contenant un médicament, une matière matricielle et un agent gonflant. Selon un aspect de l'invention, les matières particulaires multiples comprennent un noyau renfermant un médicament et un enrobage entourant le noyau. L'enrobage est choisi dans le groupe formé de (I) un enrobage sensiblement imperméable au médicament et perméable à l'eau et (ii) un enrobage anti-libération retardée.

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